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Short-term toxicity to fish

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Description of key information

The acute toxicity of the test substance 2-methylbutan-1-ol to Zebrafish (Danio rerio) was assessed according to OECD 203 under GLP conditions in a semi-static system (BASF SE, 17F0340/10E022, 2011). The 96 hour LC50 was determined to be nominal greater than 120 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
120 mg/L

Additional information

The acute toxicity of the test substance 2-methylbutan-1-ol to Zebrafish (Danio rerio) was assessed according to OECD 203 under GLP conditions in a semi-static system (BASF SE, 17F0340/10E022, 2011). The nominal test concentration was 120 mg/L and the mean measured concentration of the test substance was determined to be 112 mg/L. The 96 hour LC50 was determined to be nominal greater than 120 mg/L.

 

In addition the short-term toxicity to fish of the other category members was assessed.

 

A publication is available describing the acute toxicity of the category member 1-pentanol to Zebrafish (Danio rerio) according to OECD Draft 1980 and ISO TC 147/SCS/WG3 under Non-GLP conditions over 96 hours of exposure and under static conditions. The 96 hour LC50 was determined to be 530 mg/L based on the nominal concentration.

 

Supplementary the acute toxicity of 3-methylbutan-1-ol (another category member) to Salmo gairdneri (new name: Oncorhynchus mykiss) was assessed according to OECD 203 under static conditions. The 96 hour LC50 was determined to be nominal 700 mg/L.

 

In conclusion the 96h-LC50 value of the test substance and of the read across category members was determined to be greater than 100 mg/L.

 

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