α,α,2,6-tetrachlorotoluene

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

other information

Reliability:

2 (reliable with restrictions)

Cross-reference

Reason / purpose for cross-reference:

reference to same study

Data source

Reference

Reference Type:

publication

Title:

Toxicity of aryl- and benzylhalides to Daphnia magna and classification of their mode of action based on quantitative structure-activity relationship

Author:

Marchini, Silvia; Passerini, Laura; Hoglund Marrilynn D.; Pino Anna; Nendza, Monika

Year:

1999

Bibliographic source:

Environmental Toxicology and Chemistry (1999), 18(12), 2759-2766

Materials and methods

Principles of method if other than guideline:

Immobilisation test.

Test material

Test material information

Constituent 1

Reference substance name:

α,α,2,6-tetrachlorotoluene

EC Number:

201-332-0

EC Name:

α,α,2,6-tetrachlorotoluene

Cas Number:

81-19-6

Molecular formula:

C7H4Cl4

IUPAC Name:

1,3-dichloro-2-(dichloromethyl)benzene

Details on test material:

Source: Fluka AG (Buchs, Switzerland)

Sampling and analysis

Analytical monitoring:

yes

Test organisms

Test organisms (species):

Daphnia magna

Details on test organisms:

Age of test organisms: less than 24 hours

Study design

Total exposure duration:

48 h

Test conditions

Test temperature:

21.5 °C

pH:

8.3

Details on test conditions:

16:8 hours light:dark

Results and discussion

Effect concentrations

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

0.39 mg/L

Remarks on result:

other: 0.35 - 0.44

Applicant's summary and conclusion

Conclusions:

With the indicated test data the EC50 of 2,6-dichlorobenzal chloride to Daphnia magna under the conditions of the test was estimated to be 0.39 mg/L.