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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin sensitisation

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Administrative data

Endpoint:
skin sensitisation: in vivo (non-LLNA)
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1980

Materials and methods

GLP compliance:
no
Type of study:
guinea pig maximisation test

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-dichlorobenzoxazole
EC Number:
222-818-9
EC Name:
2,6-dichlorobenzoxazole
Cas Number:
3621-82-7
Molecular formula:
C7H3Cl2NO
IUPAC Name:
2,6-dichloro-1,3-benzoxazole

In vivo test system

Test animals

Species:
guinea pig
Strain:
other: Pirbrigh-White
Sex:
male

Study design: in vivo (non-LLNA)

Induction
Route:
intradermal
Challenge
Route:
epicutaneous, occlusive

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
sensitising
Remarks:
Migrated information
Conclusions:
It can be concluded that 2,6-Dichlorobenzoxazole is a skin sensitiser under the test conditions .