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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

The NOEC after 3 hours exposure was 180 mg/L.

Key value for chemical safety assessment

EC50 for microorganisms:
590 mg/L
EC10 or NOEC for microorganisms:
180 mg/L

Additional information

A reliable toxicity study with microorganisms is available for FX511 and is included in this dossier.


Clark (2012) conducted a reliable (Klimisch 1) GLP compliant study according to OECD 209 methods. Activated sludge was exposed to FX511 at nominal concentrations of 100, 180, 320, 560 and 1000 mg/L for 3 hours. The effect of the test item on the respiration of activated sewage sludge resulted in a 3-hour EC50 value of 590 mg/L. The NOEC after 3 hours exposure was 180 mg/L. Consequently, this value will be taken for the toxicity of FX511 to microorganisms endpoint.