Registration Dossier

Physical & Chemical properties

Boiling point

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 03/07/2012 to 24/07/2012
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
The study was conducted according to an internationally recognised method, and under GLP. The substance is considered to be adequately characterised with its purity. Validation applies, with minor restrictions due to heating rate.
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
yes
Remarks:
heating rate slightly exceed maximum of 1K/min as recommended
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
yes
Remarks:
heating rate slightly exceed maximum of 1K/min as recommended
GLP compliance:
yes (incl. certificate)
Remarks:
Inspected on 15th and 16th November 2011 / Signed on 1st May 2012
Type of method:
method according to Siwoloboff
Boiling pt.:
589 K
Atm. press.:
97.4 kPa
Decomposition:
no
Remarks on result:
other: =316°C; measured; accuracy +/-2K
Key result
Boiling pt.:
591 K
Atm. press.:
101.325 kPa
Remarks on result:
other: =318°C; corrected to normal atmospheric pressure

STAGE OF TEST TEMPERATURE (K)
PRELIMINARY TEST DETERMINATION 1 DETERMINATION 2
Beginning of measurement 580 586 586
Bubbles were emerged from the capillary 596 589 589
Atmospheric pressure (kPa) 97.4 97.4 97.4
Executive summary:

The boiling point of the test substance was determined under GLP according to OECD 103/EU A2 guideline, Siwoloboff (capillary) method. Two main runs were performed, and the mean value was corrected to normal atmP.

Measured boiling point = 316°C under 97.4 kPa; Corrected boiling point = 318°C (591K) to normal atmP

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
The study was conducted according to an internationally recognised method, and under GLP. The substance is considered to be adequately characterised with its purity. Validation applies, with minor restrictions due to heating rate.
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
yes
Remarks:
heating rate slightly exceed maximum of 1K/min as recommended
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
yes
Remarks:
heating rate slightly exceed maximum of 1K/min as recommended
GLP compliance:
no
Type of method:
method according to Siwoloboff
Boiling pt.:
600 K
Atm. press.:
96.8 kPa
Decomposition:
no
Remarks on result:
other: =327°C; measured; accuracy +/-2K
Boiling pt.:
602 K
Atm. press.:
101.325 kPa
Remarks on result:
other: =329°C; corrected to normal atmospheric pressure

STAGE OF TEST TEMPERATURE (K)
PRELIMINARY TEST DETERMINATION 1 DETERMINATION 2
Beginning of measurement 522 537 537
Bubbles were emerged from the capillary 593 600 600
Atmospheric pressure (kPa) 96.8 96.8 96.8
Executive summary:

The boiling point of the test substance was determined according to OECD 103/EU A2 guideline, Siwoloboff (capillary) method. Two main runs were performed, and the mean value was corrected to normal atmP.

Measured boiling point = 327°C under 96.8 kPa; Corrected boiling point = 329°C to normal atmP.

Description of key information

Boiling starts between 318 and 329°C (under normal atmP), depending on purity.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
318 °C

Additional information

Two reliable experimental studies, conducted according to a recognized OECD/EC method, are available. Despite minor restriction due to heating rate, both are considered as key studies, as relating to two different purities. The result for the highest purity is retained as key data for purpose of CSA.