Registration Dossier
Registration Dossier
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EC number: 219-823-3 | CAS number: 2544-13-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- No information
- Year:
- 1 972
- Bibliographic source:
- "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 348, 1972. (ChemIDplus data base)
- Reference Type:
- publication
- Title:
- No information
- Year:
- 1 997
- Bibliographic source:
- RTECS NUMBER AY5950000
Materials and methods
- Principles of method if other than guideline:
- Method not published
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Methyldopa
- EC Number:
- 209-089-2
- EC Name:
- Methyldopa
- Cas Number:
- 555-30-6
- IUPAC Name:
- 3-hydroxy-alpha-methyl-L-tyrosine
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 5 000 mg/kg bw
- Based on:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- LD50 oral rat = 5000 mg/kg
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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