N,N-bis(3-aminopropyl)methylamine

Endpoint summary

Additional information

Aquatic toxicity

Based on the available data, it can be concluded that the substance is acutely harmful to aquatic organisms.

 

Short-term toxicity to fish

The toxicity of N,N-bis(3 -aminopropyl)methylamine (CAS 105 -83 -9) was studied in a static test according to national standards (DIN 38412, part 15). The test item concentrations were not analytically verified, but are assumed to be stable regarding the low volatility. The 96 -h LC50 was determined to be 147 mg/L. In addition to the not pH-adjusted test solutions, the highest test concentration of 1000 mg/L was tested in parallel after neutralisation. This treatment had no effect on the fish, while all fish were dead after 1 h at 1000 mg/L when the pH was not adjusted (BASF AG, 1987; report no. 87/189).

In conclusion, the test substance is with high probability acutely not harmful to fish.

 

Long-term toxicity to fish

No data available.

 

Short-term toxicity to aquatic invertebrates

The acute toxicity of N,N-bis(3 -aminopropyl)methylamine (CAS 105 -83 -9) was studied in a static test according to method OECD 202. The test item concentrations were analytically verified and were stable during the exposure period (±20% of nominal). Therefore the effect concentrations are based on the nominal values. The 48-h EC50 was determined to be 18.1 mg/L (BASF SE, 2012; report no. 50E0435/11E097).

In conclusion, the substance is acutely harmful to aquatic invertebrates.

 

Long-term toxicity to aquatic invertebrates

No data available

 

Toxicity to aquatic algae and cyanobacteria

There is one reliable study available regarding the toxic effect of N,N-bis(3 -aminopropyl)methylamine (CAS 105 -83 -9). The study was performed according to OECD 201 under GLP conditions. The test species was Desmodesmus subspicatus. The test concentrations were analytically verified. The measured concentrations were ±20% of the nominal values (97% to 111% mean recovery) with an exception of the lowest test concentration (1 mg/L, nominal), which had a recovery at test start of 200% and was below the LOQ at test end. Nevertheless the effect values are based on nominal concentrations since the lowest concentrations did not show any negative effects. The 72 -h effect values are as follows: NOErC = 3.2 mg/L, ErC10 = 12.6 mg/L, ErC50 62.6 mg/L (BASF SE, 2012; report no. 60E0435/11E098).

In conclusion, the substance is acutely harmful to algae.

 

Toxicity to microorganisms

The microbial toxicity of N,N-bis(3 -aminopropyl)methylamine (CAS 105 -83 -9) was studied in a non-GLP guideline study according to ISO 8192 (respiration inhibition test with activated sludge) . The respiration inhibition test used activated sludge as inoculum taken from a wwtp treating predominantly domestic sewage. The 3 -h EC20 was determined to be greater than 1000 mg/L (BASF AG, 1990; report no. 01.89/2040).

In conclusion, the inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.