Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 907-241-9 | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Additional information
According to published data on the US EPA website 1-chlorododecane was tested in a combined oral repeated-dose/reproductive/developmental toxicity screening study. In this study administration of the test item by gavage no reproductive effects were observed. The NOAEL for reproductive effects is therefore 1000 mg/kg bw/day (highest dose tested).
According to published data on the US EPA website 1 -chlorododecane was tested in a combined oral repeated-dose/reproductive/developmental toxicity screening study. In this study administration of the test item by gavage caused developmental effects including reductions in pup survival, pup body weight and pup body weight gain at the highest dose of 1000 mg/kg bw/day. The NOAEL for developmental toxicity is 300 mg/kg bw/day. The effects observed are well within the range of maternal toxicity (LOAEL 300 mg/kg bw/day).
Justification for classification or non-classification
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
