Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1970
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1970
Report date:
1970

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
The test item has been administered to rats at dose of 1000, 2000 and 4000 mg/kg bw.
GLP compliance:
no
Test type:
standard acute method

Test material

Constituent 1
Reference substance name:
Sodium diisobutylnaphthalenesulphonate
EC Number:
248-326-4
EC Name:
Sodium diisobutylnaphthalenesulphonate
Cas Number:
27213-90-7
Molecular formula:
Not applicable (UVCB substance)
IUPAC Name:
sodium 2,3-bis(2-methylpropyl)naphthalene-1-sulfonate
Test material form:
solid: particulate/powder

Test animals

Species:
rabbit
Strain:
Vienna White
Sex:
male/female

Administration / exposure

Vehicle:
water
Duration of exposure:
24 hours
Doses:
1000, 2000 and 4000 mg/kg bw
No. of animals per sex per dose:
1000 mg/kg: 2 males and 1 female
2000 mg/kg: 2 females and 1 male
4000 mg/kg: 4 males and 2 females

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
3 000 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
LD50 for male/female rabbits is 3000 mg/kg.

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