Registration Dossier
Registration Dossier
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EC number: 248-326-4 | CAS number: 27213-90-7
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
No experimental studies regarding toxicokinetics of Sodium diisobutylnaphtalene sulphonate are available. Nevertheless available data and information derived from the testing strategy adopted for the chemical permit to evaluate main aspects of the substance toxicokinetics. Sodium diisobutylnaphtalene sulphonate is expected to be absorbed by oral and inhalation route as, in the acute and repeated toxicity studies by these routes, systemic effects have been observed. However, Sodium diisobutylnaphtalene sulphonate is expected to be present at low concentrations into the atmosphere, basing on its low vapour pressure, while it may be present dissolved into the atmospheric water. Neither systemic nor local effects were observed in the dermal acute toxicity study at the dose of 3,000 mg/kg bw. Results of this study may lead to the conclusion that the chemical is expected to have a low skin absorption.Systemic effects observed in toxicity studies do not permit to make considerations on the distribution of Sodium diisobutylnaphtalene sulphonate, however, as no histopathological lesions of the organs, with the exception of lungs in the 28-day repeated toxicity study by inhalation, have been observed, and considering the low experimental logPOW for the substance, a limited distribution or a low bioaccumulation potential can be expected for Sodium diisobutylnaphtalene sulphonate. No considerations can be made for the modalities of excretion.
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