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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2011-10-25 - 2011-10-26
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
column elution method
Specific details on test material used for the study:
- Name of test material (as cited in study report): BAEE [bis (Aminoethyl) Ether]
- Substance type: Colourless liquid
- Physical state: Liquid
- Analytical purity: 95.9%
- Composition of test material, percentage of components: 2.2% ET-bis(aminoethyl)ether, 0.5% monoethanolamine, 0.12% methoxyethylmorpholine, 0.37% water
- Lot/batch No.: LL080179
- Storage condition of test material: Sample stored in cool, well-ventilated storage area prior to testing
Key result
Water solubility:
> 1 000 g/L
Temp.:
20 °C
Remarks on result:
other: During the aqueous solubility estimation stage of the test, the sample was found to be completely miscible with water in all proportions. The pH of the mixtures was not measured.
Details on results:
Due to the infinite solubility observed, no further test was conducted. The aqeous solubility of BAEE was therefore estimated as infinite.

During the aqueous solubility estimation stage of the test, 984.3 mg of the sample completely dissolved in 0.05 mL of water.

Volume ratios of 5 mL of test material to 5 mL of water (1:1); 6 mL to 3 mL (2:1); 3 mL to 9 mL (1:3); and 6 mL to 2 mL (3:1) were also investigated but no phase separation was observed.

Conclusions:
The substance is concluded to be miscible with water in all proporations at ambient temperature.

Description of key information

In a GLP study according to the preliminary test as specified in test method EC A.6, the test substance was determined to be miscible with water in all proportions under ambient conditions (Younis S, 2012).

Key value for chemical safety assessment

Water solubility:
100 g/L
at the temperature of:
20 °C

Additional information

The substance is miscible with water in all proportions. The bounded value of 100 g/L is used as the key value for chemical safety assessment, being the maximum value for water solubility as defined in the EUSES program.