Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 306-232-1 | CAS number: 96690-38-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A study according to OECD 211 for a similar read-across substance was technically not feasible due to substance characteristics.
Key value for chemical safety assessment
Additional information
Since no studies investigating the long-term toxicity to aquatic invertebrates of Fatty acids, C16-18, 2-octyldodecyl esters (CAS 96690-38-9) are available for this endpoint, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read across to the structurally related category member 2-octyldodecyl isooctadecanoate (CAS 93803-87-3) was conducted. The read-across substance is characterized by the same alcohol component (2-octyldodecan-1-ol) and a very similar fatty acid (C16-18 compared to C18iso (target)). This read-across is justified in detail in the overall summary (IUCLID Section 6.1) and within the category justification in IUCLID Section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substances were used for the assessment. Nevertheless, as it can be seen in the data matrix of the category justification in section 13 and the overall summary, all reliable data in the category support the hazard assessment of each category member by showing a consistent pattern of results.
A statement from a laboratory is available indicating that the study with the read-across substance 2-octyldodecyl isooctadecanoate is technically not feasible due to substance characteristics (Bogers, 1998).Acute testing inDaphnia magnawas performed by exposing organisms to Water Accommodated Fractions (WAFs) (see NOTOX Project 227341 ‘Acute toxicity study inDaphnia magnawith [trade name]‘). However, it is not common practice to use this approach in a prolonged toxicity test. The use of a column generator with the test substance coated on an inert carrier (glass beads or celite) is not possible as the test substance is a liquid. The testing in a flow-through system is also no possible alternative, since the hydrophobic character of the test substance hampers any way of mixing with the dilution water. Based on the high hydrophobicity, there is no analytical method sensitive enough to detect concentrations of the test substance in water samples. As a result, it is not possible to give any analytical support to the reproduction test with Daphnia magna. This analytical support is essential to meet the acceptability criterion for evidence that the actual concentration had been maintained within a 20% window during the total test period.
Owing to the fact that the test substance is a liquid with a water solubility below detection (< 0.05 mg/L) and a log Kow of > 7, it is not possible to prepare solutions that can be tested in a 21-day reproduction test withDaphnia magna. Further, these characteristics support the expectation that it will not be very likely that bioavailable concentrations of the test substance will ever occur in the water phase, i.e. concentrations high enough to induce any acute or chronic effects in aquatic organisms.Based on the available result from one structurally related read-across substance (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) which is characterized by a similar ecotoxicological profile and comparable structure, it can be concluded that the same result is expected when testing Fatty acids, C16-18, 2-octyldodecyl esters.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
