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EC number: 292-564-1 | CAS number: 90640-45-2
Endpoint summary
Administrative data
Description of key information
Additional information
Environmental fate data of various alkyl-1,3 -diaminopropanes have been used for the evaluation of the environmental fate of Amines, N-C16-22-alkyltrimethylenedi-. The justification for the read-across is based on the similarities in their chemical structure, physico-chemical and environmental fate properties. All alkyl-1,3 -diaminopropanes under consideration consist of carbon, hydrogen and nitrogen only. The basic structure includes a hydrocarbon chain with a 1,3-propane diamine group at the end of the chain. Due to the identical position of the functional diamine group and the identical CH2 -groups adjacent to the diamine group, no difference in chemical reactivity is expected for the functional group. The only difference consists of differing chain lengths and slight variations in the degree of saturation in the alkyl chain. Therefore significant changes in chemical behavior and/or reactivity are not to be expected.
Alkyl-1,3 -diaminopropanes are protonated under ambient conditions. This means that they will sorb strongly to negatively charged substances like glassware, soil and sediment constituents. For four different soils Kd-values were observed ranging from 250 to 850 L/kg. Biodegradation is considered to be the main removal mechanism of this substance. The half-life in the different environmental compartments is expected to be short. No measured data is available which quantifies the half-life of diamines in soil or sediment. These values can therefore be estimated as a worst-case based on the readily biodegradability and the sorption data as determined in a sorption desorption test.
The observed removal in a waste water treatment simulation test was 99.4% for N-C16-18-alkyl (even-numbered) propane-1,3-diamine (CAS no. 133779-11-0) using specific chemical analyses (LC-MS/MS) during day 56 to 60 (n=5). In addition the sorption to sludge was measured and this accounted for 4.1% of the total removal which means that 95.3% was removed by biodegradation.
Diamines do not contain hydrolysable covalent bonds. Cleavage of a carbon-nitrogen bond under environmental conditions is only possible with a carbonyl group adjacent to the nitrogen atom.
Standard OECD 305 tests to assess the bioaccumulation are technically not feasible with these strongly sorbing easily degradable substances. Several attempts have been made which demonstrated that maintaining a steady state exposure at the low aquatic concentrations required is impossible. Furthermore, the route of exposure in a standard OECD 305 test is unrealistic for these substances because the substance will either be sorbed or biodegraded.
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