Registration Dossier
Registration Dossier
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EC number: 500-425-6 | CAS number: 159034-91-0 1 - 6.5 moles ethoxylated
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The concentrations of test item causing a 50% and 10% reduction at 72h in growth rate were:
72h-EC50 = 47 mg/L
72h-EC10 = 17 mg/L
NOEC = 7.1 mg/L
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 47 mg/L
- EC10 or NOEC for freshwater algae:
- 17 mg/L
Additional information
The determination of the growth inhibition of the freshwater algae Pseudokirchneriella subcapitata (previously known as Raphidocelis subcapitata and Selenastrum capricornutum) exposed to the test item for a duration of 72 hours was assessed according to the OECD Guideline 201.
Algae were exposed to 5 to 100 mg/L of test item dissolved in dilution water. The toxic effect measured during the assay was the inhibition of cellular multiplication over a time period of 72 hours.
The concentrations of test item causing 50 % reduction in biomass (EbC50) and in growth rate (ErC50) were estimated. EbC10 and ErC10 were also estimated. It was possible to determine No Observable Effect Concentrations (NOEC). The results were as follows:
72h-EbC50= 20 mg/L
72h-EbC10= 7.9 mg/L
NOECb= 3.6 mg/L
72h-ErC50= 47 mg/L
72h-ErC10= 17 mg/L
NOECr= 7.1 mg/L
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