2-amino-2-methylpropanol

Acute Toxicity: other routes

Administrative data

Endpoint:

acute toxicity: other routes

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

Not applicable

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: documentation insufficient for assessment

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1976

Report date:

1976

Materials and methods

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

2-amino-2-methylpropanol

EC Number:

204-709-8

EC Name:

2-amino-2-methylpropanol

Cas Number:

124-68-5

Molecular formula:

C4H11NO

IUPAC Name:

2-amino-2-methylpropan-1-ol

Details on test material:

- Name of test material (as cited in study report): AMP; P-1826
- Lot/batch No.: C450511

Test animals

Species:

mouse

Strain:

not specified

Sex:

female

Administration / exposure

Route of administration:

intraperitoneal

Vehicle:

water

Doses:

460, 300, 220, 180, 160 mg/kg

No. of animals per sex per dose:

Ten

Control animals:

no

Results and discussion

Effect levels

Sex:

female

Dose descriptor:

LD50

Effect level:

230 mg/kg bw

Remarks on result:

other: ±25

Any other information on results incl. tables

Not applicable

Applicant's summary and conclusion

Conclusions:

The i.p. LD50 for female mice was 230±25 mg/kg.