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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to birds

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Administrative data

toxicity to birds
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Study period:
Not applicable
3 (not reliable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
conflicting info on test substance identity (AMP or AMPD ?) no clear info on administration method (gavage ? pellets ? capsules ?) no clear info on test species

Data source

Reference Type:
The Acute Oral Toxicity, Repellency, and Hazard Potential of 998 Chemicals to One of More Species of Wild and Domestic Birds
Schafer EW, Bowles WA et al
Bibliographic source:
Arch. Environm. Contam. Toxicol. 12:355-382

Materials and methods

Principles of method if other than guideline:
acute oral testing in birds with 998 chemicals with LD50 determination
GLP compliance:

Test material

Specific details on test material used for the study:
conflicting information about what was tested (end of page 363):
- text describes as 2-Amino-2-methyl-1-propanol (which is CAS 124-68-5, AMP)
- CAS N° indicated is 115-69-5 (which corresponds to 2-Amino-2-methyl-1,3-propanediol, AMPD)
"technical and analytical grade"'
Dose method:
not specified
3 methods listed, not indicated which one was used: - gavage with solution in propylene glycol - pellets - gelatin capsules
Analytical monitoring:
unknown, see above

Test organisms

Test organisms (species):
other: probably Agelaius phoeniceus (Red-winged blackbird) but not clearly stated
Details on test organisms:
Wild-trapped birds were preconditioned to captivity for 2-6 weeks.

Results and discussion

Effect levels
Dose descriptor:
Effect level:
> 102 mg/kg bw
Basis for effect:
Remarks on result:
not measured/tested
LD50 in birds was reported to be greater than 102 mg/kg bw. No info about tested doses.
Repellency factors (if applicable):
not determined for this test chemical

Any other information on results incl. tables

No other information was available

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
AMP or AMPD (test substance unclear) is reported to have an oral LD50 greater than 102 mg/kg bw in birds (species and administration method not indicated).