Registration Dossier
Registration Dossier
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EC number: 204-709-8 | CAS number: 124-68-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to birds
Administrative data
- Endpoint:
- toxicity to birds
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- Not applicable
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: The publication provides little details about the methods used, especially on dosing for oral exposure.
Data source
Reference
- Reference Type:
- publication
- Title:
- The Acute Oral Toxicity, Repellency, and Hazard Potential of 998 Chemicals to One of More Species of Wild and Domestic Birds
- Author:
- Schafer, et.al.
- Year:
- 1 983
- Bibliographic source:
- Arch. Environ,. Contam. Toxicol. 12:355-382
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EPA OPP 71-1 (Avian Acute Oral Toxicity Test)
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-amino-2-methylpropanol
- EC Number:
- 204-709-8
- EC Name:
- 2-amino-2-methylpropanol
- Cas Number:
- 124-68-5
- Molecular formula:
- C4H11NO
- IUPAC Name:
- 2-amino-2-methylpropan-1-ol
Constituent 1
- Dose method:
- gavage
- Analytical monitoring:
- no
- Vehicle:
- yes
- Details on preparation and analysis of diet:
- Dosed via gavage with solutions of the test chemical in propylene glycol.
Test organisms
- Test organisms (species):
- other: Redwinged Blackbird
- Details on test organisms:
- Wild-trapped birds were preconditioned to captivity for 2-6 weeks.
Study design
- Limit test:
- no
- Post exposure observation period:
- No details given
Examinations
- Details on examinations and observations:
- There was no discussion of any in-life observations or pathological findings.
Results and discussion
Any other information on results incl. tables
LD50 in birds was reported to be greater than 102 mg/kg bw. No other information was available
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- LD50 in birds was reported to be greater than 102 mg/kg bw. No other information was available
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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