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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

A GLP study report the short-term toxicity of AMP to the freshwater Daphnia magna (Methods of Acute Toxicity Tests with Fish, Macroinvertebrates, and Amphibians, USEPA, 1975). Effects on the saltwater species Crangon crangon were determined under conditions similar to EPA OPPTS 850-1045. A third study on Daphnia magna is not reliable, as the study has limited documentation and does not address the endpoint after 48h of exposure.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
203 mg/L

Marine water invertebrates

Marine water invertebrates
Effect concentration:
188.4 mg/L

Additional information

The LC50 for freshwater species Daphnia magna was 193 mg/L test material with 95% AMP, while the LC50 for the saltwater shrimp Crangon crangon was 179 mg/L test material, indicating no significant different in toxicity between freshwater and saltwater inverterbrates. The EC50 for the test substance amounts to 203 mg/L AMP for Daphnia magna and 188.4 mg/L AMP for Crangon crangon. The key study corresponds to the most sensitive test species, the saltwater shrimp (Crangon crangon, EC50=188.4 mg/L).