Registration Dossier

Administrative data

Endpoint:
distribution modelling
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Study period:
Not applicable
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
There are no guidelines on how to conduct this type of modelling but the methods described are well accepted scientifically. The model used for predicting transport between environmental compartments was Level III model version 2.80 and obtained from the Canadian Environmental Modelling Center.
Cross-referenceopen allclose all
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2006
Report Date:
2006

Materials and methods

Model:
calculation according to Mackay, Level III
Calculation programme:
The model used for predicting transport between environmental compartments was Level III model version 2.80 and obtained from the Canadian Environmental Modelling Center.
Release year:
2 004
Media:
air - biota - sediment(s) - soil - water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Not applicable

Results and discussion

Percent distribution in media

Air (%):
0.1
Water (%):
99.9
Soil (%):
0.1
Sediment (%):
0.1

Any other information on results incl. tables

Level III: Predicted distribution among air, water, soil, and sediments

 

Emission Scenario

Percentage and amount distributed to

Residence Time (days)

[without advection in brackets]

Air

Water

Soil

Sediment

1,000 kg/hr to Air

 0.5%

2770 kg

59.1%

3.58 x 105kg

40.5%

2.45 x 105kg

<0.1%

142 kg

25

[ 44]

1,000 kg/hr to Water

<0.1%

2 kg

99.9%

8.38 x 105 kg

<0.1%

144 kg

<0.1 %

333 kg

35

[216]

1,000 kg/hr to Soil

<0.1%

278 kg

58.1%

7.49 x 105kg

41.8%

5.39 x 105kg

<0.1%

298 kg

54

[220]

1,000 kg/hr simultaneously to Air, Water, and Soil

 0.1%

3050 kg

71.2%

1.94 x 106kg

28.7%

7.84 x 105kg

<0.1%

773 kg

38

[116]

Highlighted scenario indicates most probable emission route, based on physical properties and use patterns.

 

Applicant's summary and conclusion

Conclusions:
This substance has high water solubility, a low vapor pressure, and low log Kow. The substance has a low potential for adsorption to soil or sediments, and a low potential to volatilize from water or soil to the atmosphere. If released to air, the substance will react with hydroxyl radicals. If released directly to water, the most probable emission route based on physical properties and use patterns, most of the substance will remain in the water compartment and is expected to be biodegraded. If released to soil, the substance is expected to be biodegraded.
Executive summary:

The environmental distribution and transport of 2-amino-2-methyl-1-propanol (AMP) between environmental compartments (air, water, soil, and sediments) was predicted using Level I and Level III fugacity models. Input values required for the Level I model include molecular weight, melting point, water solubility, vapor pressure, and octanol/water partition coefficient.  In addition to these parameters, the Level III model requires input of measured or estimated half-lives for reaction in air, water, soil, and sediments. The Level I model estimates the Henry’s Law constant for the compound, and predicts the distribution of the compound between the environmental compartments assuming that equilibrium is attained. The Level III model incorporates transport rates into and between environmental compartments, and allows for losses of the compound due to advection or degradation processes. 

 

AMP hashigh water solubility, a low vapor pressure, and low log Kow. The substance has a low potential for adsorption to soil or sediments, and a moderate potential to volatilize from water or soil to the atmosphere. If released to air, the substance will react with hydroxyl radicals. If released directly to water, the most probable emission route based on physical properties and use patterns, most of the substance will remain in the water compartment and is expected to be biodegraded. If released to soil, the substance is expected to be biodegraded.