2-amino-2-methylpropanol

Distribution modelling

Administrative data

Endpoint:

distribution modelling

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

supporting study

Study period:

Not applicable

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

There are no guidelines on how to conduct this type of modelling but the methods described are well accepted scientifically. The model used for predicting transport between environmental compartments was Level III model version 2.80 and obtained from the Canadian Environmental Modelling Center.

Data source

Reference

Reference Type:

other company data

Title:

Unnamed

Year:

2006

Report date:

2006

Materials and methods

Model:

calculation according to Mackay, Level III

Calculation programme:

The model used for predicting transport between environmental compartments was Level III model version 2.80 and obtained from the Canadian Environmental Modelling Center.

Release year:

2 004

Media:

air - biota - sediment(s) - soil - water

Test material

Test material information

Constituent 1

Reference substance name:

2-amino-2-methylpropanol

EC Number:

204-709-8

EC Name:

2-amino-2-methylpropanol

Cas Number:

124-68-5

Molecular formula:

C4H11NO

IUPAC Name:

2-amino-2-methylpropan-1-ol

Details on test material:

Not applicable

Results and discussion

Percent distribution in media

Air (%):

0.1

Water (%):

99.9

Soil (%):

0.1

Sediment (%):

0.1

Any other information on results incl. tables

Level III: Predicted distribution among air, water, soil, and sediments

Emission Scenario	Percentage and amount distributed to				Residence Time (days) [without advection in brackets]
	Air	Water	Soil	Sediment
1,000 kg/hr to Air	0.5% 2770 kg	59.1% 3.58 x 10^5kg	40.5% 2.45 x 10^5kg	<0.1% 142 kg	25 [ 44]
1,000 kg/hr to Water	<0.1% 2 kg	99.9% 8.38 x 10^5 kg	<0.1% 144 kg	<0.1 % 333 kg	35 [216]
1,000 kg/hr to Soil	<0.1% 278 kg	58.1% 7.49 x 10^5kg	41.8% 5.39 x 10^5kg	<0.1% 298 kg	54 [220]
1,000 kg/hr simultaneously to Air, Water, and Soil	0.1% 3050 kg	71.2% 1.94 x 10^6kg	28.7% 7.84 x 10^5kg	<0.1% 773 kg	38 [116]

Highlighted scenario indicates most probable emission route, based on physical properties and use patterns.

 

Applicant's summary and conclusion

Conclusions:

This substance has high water solubility, a low vapor pressure, and low log Kow. The substance has a low potential for adsorption to soil or sediments, and a low potential to volatilize from water or soil to the atmosphere. If released to air, the substance will react with hydroxyl radicals. If released directly to water, the most probable emission route based on physical properties and use patterns, most of the substance will remain in the water compartment and is expected to be biodegraded. If released to soil, the substance is expected to be biodegraded.

Executive summary:

The environmental distribution and transport of 2-amino-2-methyl-1-propanol (AMP) between environmental compartments (air, water, soil, and sediments) was predicted using Level I and Level III fugacity models. Input values required for the Level I model include molecular weight, melting point, water solubility, vapor pressure, and octanol/water partition coefficient.  In addition to these parameters, the Level III model requires input of measured or estimated half-lives for reaction in air, water, soil, and sediments. The Level I model estimates the Henry’s Law constant for the compound, and predicts the distribution of the compound between the environmental compartments assuming that equilibrium is attained. The Level III model incorporates transport rates into and between environmental compartments, and allows for losses of the compound due to advection or degradation processes. 

 

AMP hashigh water solubility, a low vapor pressure, and low log K_ow. The substance has a low potential for adsorption to soil or sediments, and a moderate potential to volatilize from water or soil to the atmosphere. If released to air, the substance will react with hydroxyl radicals. If released directly to water, the most probable emission route based on physical properties and use patterns, most of the substance will remain in the water compartment and is expected to be biodegraded. If released to soil, the substance is expected to be biodegraded.