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EC number: 204-709-8 | CAS number: 124-68-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Distribution modelling
Administrative data
- Endpoint:
- distribution modelling
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- supporting study
- Study period:
- Not applicable
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- There are no guidelines on how to conduct this type of modelling but the methods described are well accepted scientifically. The model used for predicting transport between environmental compartments was Level III model version 2.80 and obtained from the Canadian Environmental Modelling Center.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
- Model:
- calculation according to Mackay, Level III
- Calculation programme:
- The model used for predicting transport between environmental compartments was Level III model version 2.80 and obtained from the Canadian Environmental Modelling Center.
- Release year:
- 2 004
- Media:
- air - biota - sediment(s) - soil - water
Test material
- Reference substance name:
- 2-amino-2-methylpropanol
- EC Number:
- 204-709-8
- EC Name:
- 2-amino-2-methylpropanol
- Cas Number:
- 124-68-5
- Molecular formula:
- C4H11NO
- IUPAC Name:
- 2-amino-2-methylpropan-1-ol
- Details on test material:
- Not applicable
Constituent 1
Results and discussion
Percent distribution in media
- Air (%):
- 0.1
- Water (%):
- 99.9
- Soil (%):
- 0.1
- Sediment (%):
- 0.1
Any other information on results incl. tables
Level III: Predicted distribution among air, water, soil, and sediments
Emission Scenario |
Percentage and amount distributed to |
Residence Time (days) [without advection in brackets] |
|||
Air |
Water |
Soil |
Sediment |
||
1,000 kg/hr to Air |
0.5% 2770 kg |
59.1% 3.58 x 105kg |
40.5% 2.45 x 105kg |
<0.1% 142 kg |
25 [ 44] |
1,000 kg/hr to Water |
<0.1% 2 kg |
99.9% 8.38 x 105 kg |
<0.1% 144 kg |
<0.1 % 333 kg |
35 [216] |
1,000 kg/hr to Soil |
<0.1% 278 kg |
58.1% 7.49 x 105kg |
41.8% 5.39 x 105kg |
<0.1% 298 kg |
54 [220] |
1,000 kg/hr simultaneously to Air, Water, and Soil |
0.1% 3050 kg |
71.2% 1.94 x 106kg |
28.7% 7.84 x 105kg |
<0.1% 773 kg |
38 [116] |
Highlighted scenario indicates most probable emission route, based on physical properties and use patterns.
Applicant's summary and conclusion
- Conclusions:
- This substance has high water solubility, a low vapor pressure, and low log Kow. The substance has a low potential for adsorption to soil or sediments, and a low potential to volatilize from water or soil to the atmosphere. If released to air, the substance will react with hydroxyl radicals. If released directly to water, the most probable emission route based on physical properties and use patterns, most of the substance will remain in the water compartment and is expected to be biodegraded. If released to soil, the substance is expected to be biodegraded.
- Executive summary:
The environmental distribution and transport of 2-amino-2-methyl-1-propanol (AMP) between environmental compartments (air, water, soil, and sediments) was predicted using Level I and Level III fugacity models. Input values required for the Level I model include molecular weight, melting point, water solubility, vapor pressure, and octanol/water partition coefficient. In addition to these parameters, the Level III model requires input of measured or estimated half-lives for reaction in air, water, soil, and sediments. The Level I model estimates the Henry’s Law constant for the compound, and predicts the distribution of the compound between the environmental compartments assuming that equilibrium is attained. The Level III model incorporates transport rates into and between environmental compartments, and allows for losses of the compound due to advection or degradation processes.
AMP hashigh water solubility, a low vapor pressure, and low log Kow. The substance has a low potential for adsorption to soil or sediments, and a moderate potential to volatilize from water or soil to the atmosphere. If released to air, the substance will react with hydroxyl radicals. If released directly to water, the most probable emission route based on physical properties and use patterns, most of the substance will remain in the water compartment and is expected to be biodegraded. If released to soil, the substance is expected to be biodegraded.
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