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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
Not applicable
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1992
Reference Type:
study report
Title:
Unnamed
Year:
1989
Report date:
1989

Materials and methods

Principles of method if other than guideline:
screening BCF over 3 days
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2-amino-2-methylpropanol
EC Number:
204-709-8
EC Name:
2-amino-2-methylpropanol
Cas Number:
124-68-5
Molecular formula:
C4H11NO
IUPAC Name:
2-amino-2-methylpropan-1-ol
Specific details on test material used for the study:
Details on properties of test surrogate or analogue material (migrated information):
Not applicable
Radiolabelling:
yes

Test solutions

Vehicle:
yes
Details on preparation of test solutions, spiked fish food or sediment:
14-C-labeled chemical was dissolved in the water at a concentration of 50ppb

Test organisms

Test organisms (species):
Leuciscus idus

Study design

Route of exposure:
aqueous
Test type:
static
Water / sediment media type:
natural water: freshwater
Total exposure / uptake duration:
3 d

Test conditions

Details on test conditions:
Five Gold orfes were raised in a test vessel with 8L of water, in which the 14-C-labeled chemical was dissolved at a concentration of 50ppb. The fish were not fed during the 3-day test. The vessel was closed and the water surface was stirred with a blade stirrer gently to provide air exchange and movement of water.
Details on estimation of bioconcentration:
At the end of the experiment, the concentration of AMP was determined by measuring the radioactivity of the fish and in the water and, from that, the accumulation factor was determined.

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
< 1
Remarks on result:
other: no bioaccumulation
Remarks:
Conc.in environment / dose:50 ppb

Applicant's summary and conclusion