Registration Dossier
Registration Dossier
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EC number: 201-756-6 | CAS number: 87-60-5
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 985
- Reference Type:
- secondary source
- Title:
- BUA Stoffbericht 55: Chlortoluidine (3-Chlor-2-methylanilin, 5-Chlor-2-methylanilin, 3-Chlor-4-methylanilin)
- Author:
- BUA Beratergremium für umweltrelevante Altstoffe
- Year:
- 1 990
- Bibliographic source:
- Verlag Chemie Weinheim 1991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- GLP compliance:
- yes
- Test type:
- standard acute method
Test material
- Reference substance name:
- 3-Chlor-2-methylanilin
- IUPAC Name:
- 3-Chlor-2-methylanilin
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- CMC (carboxymethyl cellulose)
- Doses:
- 316, 464, 681, 1000
- No. of animals per sex per dose:
- 5 male + 5 female
Results and discussion
Effect levelsopen allclose all
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- 754 mg/kg bw
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- 681 mg/kg bw
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- 681 mg/kg bw
Any other information on results incl. tables
At highest Dose of 1000 mg/kg all animals died within 1 day.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
