3-chloro-o-toluidine

Toxicity to microorganisms

Administrative data

Endpoint:

activated sludge respiration inhibition testing

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Well documented guideline study under GLP-conditions

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1990

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test

Deviations:

yes

Remarks:

other reference substance

Principles of method if other than guideline:

instead of 3,5-dichlorophenol as reference substance potassium dichromate was used in a concentration which results in 50 % inhibition.

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

3-chloro-o-toluidine

EC Number:

201-756-6

EC Name:

3-chloro-o-toluidine

Cas Number:

87-60-5

Molecular formula:

C7H8ClN

IUPAC Name:

3-chloro-2-methylaniline

Sampling and analysis

Analytical monitoring:

not required

Test solutions

Vehicle:

not specified

Test organisms

Test organisms (species):

activated sludge, domestic

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

3 h

Dose descriptor:

EC10

Effect conc.:

< 58 mg/L

Effect concentrations 2

Duration:

3 h

Dose descriptor:

EC50

Effect conc.:

130 mg/L

Effect concentrations 3

Duration:

3 h

Dose descriptor:

other: EC 80

Effect conc.:

330 mg/L