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Short-term toxicity to aquatic invertebrates

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Description of key information

48 h EC50 = 540 mg/L; 48 h NOEC = 220 mg/L, Daphnia magna , EPA OPP 72-2, EPA OTS 797.1300, Collins 1992b

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
540 mg/L

Additional information

The acute toxicity of the test material to aquatic invertebrates was investigated inDaphnia magnain accordance with the standardised guidelines EPA OPP 72-2 and EPA OTS 797.1300. During the test the daphnia were exposed to the test material at nominal test concentrations of 0, 130, 220, 360, 600 and 1000 mg/L under static renewal conditions; all tests were conducted using water soluble fractions. Based on the nominal concentrations of test material, the 48 hour EC50 value and corresponding 95% confidence interval were determined to be 540 (430 - 660) mg/L. The No Observed Effect Concentration was determined to be 220 mg/L. The study was performed in line with GLP and accepted standardised guidelines with a high standard of reporting. However, it is scored a Klimisch 2, reliable with restriction, based on potential solubility issues in the preparation of the test material solution.