Registration Dossier
Registration Dossier
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EC number: 242-894-7 | CAS number: 19224-26-1
Endpoint summary
Administrative data
Description of key information
Key data is available for propylene glycol dibenzoate (PGDB). This data is supported by relevant information available from a structural analogue Dipropylene glycol dibenzoate (DPGDB). The justification for read across is presented as an attachment included in Section 13 of the IUCLID dossier.
Biodegradation in water: screening tests
Mean oxygen consumption in mixtures containing PGDB was 7% of the theoretical value (25 mgO2/500 mL) after 1 day, 32% after 2 days, 60% after 7 days and 81% at the end of the test (Day 28). Therefore, PGDB was considered to be readily biodegradable under the conditions of the OECD Guideline 301 F, Ready Biodegradability: Manometric Respirometry Test (Huntingdon Life Sciences, 2014c; Klimisch score = 1).
In a modified Sturm test (Huntingdon Life Sciences, 1998a; Klimisch score = 1), DPGDB was found to have degraded by 6% after 2 days, 62% after 12 days, and by 85% at the end of the 28 -day biotic phase of the test.
Substances are considered to be readily degradable in this test if CO2 production is equal to or greater than 60% of the theoretical value within ten days of the level achieving 10%. In the Modified Sturm test, DPGDB met these criteria, so may be considered to be readily biodegradable. The BOD / COD studies show DPGDB to be inherently biodegradable and the anaerobic study showed it to be anaerobically biodegradable.
Biodegradation in water and sediment: simulation tests
In accordance with the adaptations found in column 2 of Annex IX, simulation studies of biodegradation in water and sediments are waived due to the demonstrated ready biodegradation of the substance.
Biodegradation in soil
In accordance with the adaptations found in column 2 of Annex IX, simulation studies of biodegradation in soils are waived due to the demonstrated ready biodegradation of the substance.
Additional information
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