Registration Dossier

Administrative data

Key value for chemical safety assessment

Effects on fertility

Effect on fertility: via oral route
Endpoint conclusion:
no study available
Effect on fertility: via inhalation route
Endpoint conclusion:
no adverse effect observed
Effect on fertility: via dermal route
Endpoint conclusion:
no study available
Additional information

A data waiving is claimed for toxicity to reproduction for (2,4,6-trioxotriazine-1,3,5(2H,4H,6H)-triyl)tris(hexamethylene) isocyanate. A full and detailed text elaborating the data waiving is attached to this endpoint summary.

 


Justification for selection of Effect on fertility via inhalation route:
No study selected, since based on read-across two reproductive toxicity screenings are available, and both are considered relevant for assessment.

Effects on developmental toxicity

Effect on developmental toxicity: via oral route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via inhalation route
Endpoint conclusion:
no adverse effect observed
Effect on developmental toxicity: via dermal route
Endpoint conclusion:
no study available
Additional information

A data waiving is claimed for developmental toxicity for (2,4,6-trioxotriazine-1,3,5(2H,4H,6H)-triyl)tris(hexamethylene) isocyanate. A full and detailed text elaborating the data waiving is attached to this endpoint summary.


Justification for selection of Effect on developmental toxicity: via inhalation route:
No study is selected, since three fully reliable developmental toxicity studies are available based on read across, and are all considered relevant for assessment.

Justification for classification or non-classification

No classification is required for toxicity to reproduction according to Regulation (EC) No 1272/2008, Annex I.