Registration Dossier
Registration Dossier
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EC number: 309-886-6 | CAS number: 101316-84-1 A tar obtained from low temperature carbonization and low temperature gasification of brown coal. Composed primarily of aliphatic, naphthenic and cyclic aromatic hydrocarbons, heteroaromatic hydrocarbons and cyclic phenols.
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
Based on the positive results of LLNA study the test substance may be a potential contact allergen, but the irritation effect observed does not rule out the possibility that it may be a false positive result.
Migrated from Short description of key information:
The Local Lymph Node Assay (LLNA) with radionuclides was used. The testing was conducted according to the EU Method B.42, Skin sensitization: Local Lymph Node Assay, Council Regulation (EC) No. 440/2008, published in O.J. L142, 2008.
GLP study
Justification for classification or non-classification
On the basis of LLNA test results, the subsatnce Tar, brown-coal, low-temp. - should be classified as skin sensitising substance - Skin Sens. 1; H317 May cause an allergic skin reaction - according to Regulation (EC) No 1272/2008 criteria (R43 May cause sensitisation by skin contact - according to DSD criteria).
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