Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

Based on the positive results of LLNA study the test substance may be a potential contact allergen, but the irritation effect observed does not rule out the possibility that it may be a false positive result.


Migrated from Short description of key information:
The Local Lymph Node Assay (LLNA) with radionuclides was used. The testing was conducted according to the EU Method B.42, Skin sensitization: Local Lymph Node Assay, Council Regulation (EC) No. 440/2008, published in O.J. L142, 2008.
GLP study

Justification for classification or non-classification

On the basis of LLNA test results, the subsatnce Tar, brown-coal, low-temp. - should be classified as skin sensitising substance - Skin Sens. 1; H317 May cause an allergic skin reaction - according to Regulation (EC) No 1272/2008 criteria (R43 May cause sensitisation by skin contact - according to DSD criteria).