Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

EC/EL50 >LoS (expert judgement and read-across)

Key value for chemical safety assessment

Additional information

No data are available for the short term toxicity to aquatic invertebrates with Alcohols, C16-17, branched and linear. The short term toxicity to aquatic imvertebrates has been estimated by read-across and expert judgement to be above the limit of solubility (LoS). Alcohols, C16-17, branched and linear is made up of C16 and 17 branched and linear alcohols. Across the alcohols category it is possible to see from Table 1 that no short term toxicity to invertebrate is achieved at the LoS for alcohols ¿C14.
From Table 2, it is possible to see that the EC(EL)50 values are not achieved for Alcohols,
C14-15, branched and linear. Since the water solubility decreases with increasing chain length, also for UVCB alcohols in table 2, and given the compoistion of the substance, it is safe to predict that EC(EL)50 would not be achieved at the LoS.

 

Table 1. Estimated acute toxicity to algae for essentially pure commercial products (using expert judgment where no data are available).

 

CAS #

Comment1

Water solubility (mg/L)

Fish LC50 (mg/L)2

Invert EC50 (mg/L)2

Algae EC50 (mg/L)2

111-27-3

6

5900 at 20°C

97

201

80

111-70-6

7¿ SUPPORTING

1313 at 20°C

38

82

 

111-87-5

8

551 at 25°C

13

20

6.5 (biomass)-14 (growth)

143-08-8

9

128 at 20 °C

5.5

25

1.0-10 (r-a)

112-30-1

10

39.5

2.3

3.1

1.0-10 (r-a)

112-42-5

11

8.0 at 20°C

1.0

0.8

0.1-1.0 (r-a)

112-53-8

12

1.93 at 20°C

1.0

0.77

0.62 (biomass) 2.6 (growth)

112-70-9

13 ¿ SUPPORTING

0.38 at 20°C

>0.33

No effects expected at LoS3

0.1-1.0 (r-a)

112-72-1

14

0.191 at 25°C

LC50 not reached

>LoS

4

(>LoS)

EC50 not reached >LoS

629-76-5

15

0.102 at 25°C

No effects expected at LoS3

No effects expected at LoS3

>0.047 (r-a C15 branched)

36653-82-4

16

0.013 at 25°C

LC50 not reached

>LoS

No effects expected at LoS3

EC50 not reached >LoS

112-92-5

18

0.0011 at 25°C

LC50 not reached

EC50 not reached

>LoS

EC50 not reached

>LoS

143-28-2

18 (unsaturated)

0.009 mg/L [estimated]

No effects expected at LoS4

No effects expected at LoS4

No effects expected at LoS (r-a)

629-96-9

20

Ca. 0.001 mg/L [estimated]

No effects expected at LoS3

No effects expected at LoS3

No effects expected at LoS (r-a)

661-19-8

22

Ca. 0.001 mg/L [estimated]

LC50 not reached

>LoS

No effects expected at LoS3

No effects expected at LoS (r-a)

506-51-4

24

Ca. 0.001 mg/L [estimated]

LC50 not reached

>LoS (r-a from C22)

No effects expected at LoS3

No effects expected at LoS (r-a)

 

Notes:

1 ¿ compositional Types are discussed in CSR

2 ¿ LoS = Limit of solubility.

3 ¿ estimated using QSAR (see CSR)

4 ¿ estimated using QSAR method and read-across from C16-18 and 18 unsaturated.

n/a ¿ not available

Unless specified read-across has occurred from the same substance data and different taxonomic groups.

 

Table 2. Estimated acute toxicity to algae for multi-constituent alcohols commercial products (using expert judgment where no data are available).

 

MCS #

Comment1

Water solubility (mg/L)

Fish LC50 (mg/L)2

Invert EC50 (mg/L)2

Algae EC50 (mg/L)2

1

Alcohols, C7-9-linear and branched

510 mg/l at a loading rate of 1000 mg/l [estimated]

0.7-0.8

5.9

3.1

2

Alcohols, C9-11-linear and branched

44 mg/l at a loading rate of 1000 mg/l. [estimate]

6.3-10

7

2.7

12

Nonanolbranched

121 mg/L [estimated]

5.5 (r-a from C9)

25 (r-a from C9)

1.0-10 (r-a)

 

Decanol, branched

38.9 mg/L

2.3 (r-a from C10)

3.1 (r-a from C10)

1.0-10 (r-a)

 

Decanol, branched and linear

26.17 mg/L at 20°C

2.3 (r-a from C10)

3.1 (r-a from C10)

1.0-10 (r-a)

10

Undecanol, linear and branched

6.3 at 25°C

1.0 (r-a from C11)

0.8 (r-a from C11)

1.0-10 (r-a)

4

Alcohols, C12-13, branched and linear

2.9-3.1 mg/L at 20°C

2.8

15 WAFs (>LoS)

ErC50 0.44

EbC50 0.23

NOEC 0.058

5

Alcohols, C12-15, branched and linear

0.8 mg/L

>LoS

<1 WAFs

ErL50 0.085-0.097

EbL50 0.039-0.045

NOEL 0.003

3

Alcohols, C12-13, branched and linear

2.4 mg/L at 25oC

4.0-10 as WAFs (>LoS)

0.23 as WAFs

ErL50 0.23

EbL50 0.084

NOEL 0.03

6/7

Alcohols, C14-15, branched and linear

0.7 mg/l at 20°C and

0.15 mg/l at a loading rate of 1000 mg/l. [estimated]

>500 (n)

>0.7 (n)

 

(both >LoS)

0.13-0.29

ErL50 22-46

EbL50 22-46

NOEL 4.6

8/9

Alcohols, C16-17, branched and linear

Ca. 0.1-0.4 mg/L (r-a from C16-17, monobranched)

>LoS (r-a from C16)

>LoS (r-a from C16)

>LoS (r-a from C16)

 

Notes:

1 ¿ compositional Types are discussed in CSR

2 ¿ LoS = Limit of solubility.

3 ¿ estimated using QSAR (see CSR)

4 ¿ estimated using QSAR method and read-across from C16-18 and 18 unsaturated.

n/a ¿ not available

WAFs ¿ water accommodated fractions

Unless specified read-across has occurred from the same substance data and different taxonomic groups.