Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Bioaccumulation: aquatic / sediment

Waiving argument

According to Annex IX, column 2 of REACH, the study does not need to be conducted as the substance has a low potential for bioaccumulation (log Kow <3). Nevertheless, QSAR results are available.

Supporting model predictions

Using CATALOGIC BCF base line model the log BCF was calculated to be 0.3816 ± 0.116 (BCF 2.4) taking into account mitigating factors. Without mitigating factors the log BCF was calculated to be 1.025 (BCF 10.58). The substance fulfils the general properties requirements of the model, the substance is in the interpolation structural space and the substance is in the mechanistic domain of the model. In conclusion the substance is in the applicability domain of the model. Thus, the result of the prediction was regarded as reliable.

 

Based on the results it was concluded that accumulation in organisms is not to be expected.