Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

 

Stability

Phototransformation in air

Model prediction

Using AOP Program (v1.92) of EPISuite software the aerobic degradation was assessed. The overall OH rate constant was calculated to be 126.0750 E-12 cm3/molecule-sec and the half-life was calculated to be 1.018 h. The substance is not within the applicability domain of the model and the estimated values are presumably highly uncertain. Nevertheless, taking the criteria of the FOCUS air report (2006) into account it was concluded that after evaporation or exposure to the air, the substance will be rapidly degraded by photochemical processes.

Hydrolysis

According to column 2 of Regulation (EC) 1907/2006, Annex VIII,section 9.2.2.1 a study on hydrolysis does not need to be conducted as the substance is readily biodegradable.

Furthermore according to Kollig et al. (1993), Boethling & Mackay (2000) and Harris (1990), the test substance is generally resistant to hydrolysis because it does not contain any labile functional groups. Therefore, no study on hydrolysis is performed.

 

Biodegradation

Biodegradation in water: screening test

The ready biodegradability of the surrogate test substance 3-Diethylaminopropylamine was determined according to the OECD guideline 301A (1993). The test substance was biodegraded by an average of 90-100 % over the test period of 28 days. Under the test conditions the surrogate test substance was found to be ready biodegradable according to OECD criteria.

Biodegradation in water and sediment: simulation test

In accordance with column 2 of REACH Regulation (EC) No 1907/2006, Annex IX, section 9.2.1.2 and section 9.2.1.4, no study on biodegradation in water and sediment needs to be conducted if the test substance is biodegradable under enhanced conditions. A read across study on the read across substance 3-Diethylaminopropylamine demonstrate that the surrogate substance is biodegradable. Thus no further biodegradation testing in water and sediment is required.

Biodegradation in soil

In accordance with column 2 of REACH Regulation (EC) No 1907/2006, Annex IX, Section 9.2.1.3, no study on biodegradation in soil needs to be conducted if the test substance is biodegradable under enhanced conditions. A read across study on the read across substance 3-Diethylaminopropylamine demonstrate that the surrogate substance is biodegradable. Thus no further biodegradation testing in soil is required.

 

Bioaccumulation

Bioaccumulation: aquatic / sediment

Waiving argument

According to Annex IX, column 2 of REACH, the study does not need to be conducted as the substance has a low potential for bioaccumulation (log Kow <3). Nevertheless, QSAR results are available.

Supporting model predictions

Using BCF base line model the log BCF was calculated to be 0.3816 ± 0.116. The substance fulfills the general properties requirements of the model, the substance is in the interpolation structural space and the substance is in the mechanistic domain of the model. In conclusion the substance is in the applicability domain of the model. Thus, the result of the prediction was regarded as reliable.

 Based on the results it was concluded that accumulation in organisms is not to be expected.

 

Transport and distribution

Adsorption

Adsorption to solid soil phase is not expected.

 

Henry´s Law constant

The substance will not evaporate into the atmosphere from the water surface