Registration Dossier
Registration Dossier
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EC number: 202-844-7 | CAS number: 100-36-7
Dissociation constant
Administrative data
Link to relevant study record(s)
Description of key information
pKa1 = 9.91 at 23 °C
pKa2 = 6.69 at 23 °C
Key value for chemical safety assessment
Additional information
A study was conducted (BASF AG 98L00765) according to OECD TG 112 to determine the dissociation constants in water of the substance. The test was done in triplicate. The first equivalence point was determined to be at pKa = 9.91 and the second equivalence point was determined to be pKa=6.69. The test was performed at 23 °C. In addition Naesaenen et al. 1963 (REAXYS 2014A) reports the dissociation constants in water to be at pKa1 = 9.51 at 25 °C and pKa2 = 6.513 at 25 °C. Lowry 1932 (REAXYS 2014B) reports the dissociation constants in water to be at pKa1 = 9.88 at 25 °C and pKa2 = 6.82 at 25 °C. The literature values support the experimental value. Thus, a pKa1 of 9.91 and pKa2 of 6.69 was chosen as key value for chemical safety assessment.
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