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Long-term toxicity to fish

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Description of key information

The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish. 

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The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish. Thus, in accordance to Annex IX, column 2 no further long-term toxicity test to fish is proposed. The available experimental studies on aquatic toxicity of2,2-bis(hydroxymethyl)-1,3-propanediyl dioleate (CAS 25151-96-6)do not show any acute toxic effects up to the limit of water solubility. Furthermore, the long term test on the reproduction of daphnids of the read across substance also does not reveal any adverse effects.Asthere was no sign that fish are the most sensitive species in the short term tests, it cannot be expected that a long-term test with fish will generate different results than the existing long-term test with invertebrates. Hence due to animal welfare reasons and to avoid unnecessary vertebrate tests, no further long-term test with fish is required for2,2-bis(hydroxymethyl)-1,3-propanediyl dioleate (CAS 25151-96-6).In addition,due to its ready biodegradability it is not likely that aquatic organisms are exposed to the test substance since it will be ultimately degraded in sewage treatment plants. Therefore, it can be concluded that chronic exposure of2,2-bis(hydroxymethyl)-1,3-propanediyl dioleate (CAS 25151-96-6)to fish is unlikely and that it would not pose a higher risk to fish than it does to daphnids.