Registration Dossier
Registration Dossier
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EC number: 263-214-5 | CAS number: 61792-11-8
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- No data
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
- Report date:
- 1976
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- A single concentration of 5g/kg/bw was applied to the skin of 10 rabbits and skin reactions recored for 14 days following exposure to the test item.
- GLP compliance:
- no
- Remarks:
- Study predates GLP
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- (2Z/6Z)-3,7-dimethylnona-2,6-dienenitrile
- Molecular formula:
- C11H17N
- IUPAC Name:
- (2Z/6Z)-3,7-dimethylnona-2,6-dienenitrile
- Reference substance name:
- (2Z/6E)-3,7-dimethylnona-2,6-dienenitrile
- Molecular formula:
- C11H17N
- IUPAC Name:
- (2Z/6E)-3,7-dimethylnona-2,6-dienenitrile
- Reference substance name:
- (2E/6Z)-3,7-dimethylnona-2,6-dienenitrile
- Molecular formula:
- C11H17N
- IUPAC Name:
- (2E/6Z)-3,7-dimethylnona-2,6-dienenitrile
- Reference substance name:
- (2E/6E)-3,7-dimethylnona-2,6-dienenitrile
- Molecular formula:
- C11H17N
- IUPAC Name:
- (2E/6E)-3,7-dimethylnona-2,6-dienenitrile
- Reference substance name:
- (3E/6Z)-3,7-dimethylnona-3,6-dienenitrile
- Molecular formula:
- C11H17N
- IUPAC Name:
- (3E/6Z)-3,7-dimethylnona-3,6-dienenitrile
- Reference substance name:
- (3E/6E)-3,7-dimethylnona-3,6-dienenitrile
- Molecular formula:
- C11H17N
- IUPAC Name:
- (3E/6E)-3,7-dimethylnona-3,6-dienenitrile
- Test material form:
- liquid
Constituent 1
Constituent 2
Constituent 3
Constituent 4
impurity 1
impurity 2
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Lemonile
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No data available
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Details on dermal exposure:
- No data available
- Duration of exposure:
- No data
- Doses:
- 5000 mg/kg bw
- No. of animals per sex per dose:
- 10
- Control animals:
- not specified
- Details on study design:
- No data available
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Based on:
- not specified
- Mortality:
- 0/10 animals died during the experiment.
- Clinical signs:
- other: No symptoms were observed
- Gross pathology:
- No data
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The acute dermal LD50 in rabbits was >5000 mg/kg bw.
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