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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

 Readily Biodegradable, 74.4 % after 28 days, OECD 301 C, Yoshikawa 1993.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

The key study (Yoshikawa, 1993) was performed using the read across substance, sodium 5-oxo-DL-prolinate, which is a racemic mixture of the D- and L- isomeric forms of the substance. Read-across is considered to be suitable based on the structural similarities between the read across substance (sodium 5-oxo-DL-prolinate) and the substance to be registered (sodium 5-oxo-L-prolinate), which is the L- isomer only. As such the difference in isomeric forms of the substance is unlikely to affect the biodegradability of the substance. The key study is a non GLP study performed to standardised guidelines with a sufficient level of detail to assess the quality of the submitted data. Sufficient details were reported to assess the quality of the submitted results. The study was assigned a reliability score of 2 in line with the principles for assessing data quality as defined by Klimisch (1997).  Under the conditions of the study, the test material degraded by 74.4 % after 28 days and was determined to be readily biodegradable.