Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin irritation / corrosion
Remarks:
other: In silico prediction.
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
June, 2010
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Skin irritation module estimates the potential of a compound to cause skin irritation in a standard rabbit Draize test.
Tox Boxes 2.9 is the in house software for the prediction of basic toxicity endpoints in chemicals. Predictions are made analyzing the chemical structure and based upon large validated databases and QSAR models, in combination with expert knowledge of organic chemistry and toxicology.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3-aminopropane-1-sulphonic acid
EC Number:
222-977-4
EC Name:
3-aminopropane-1-sulphonic acid
Cas Number:
3687-18-1
Molecular formula:
C3H9NO3S
IUPAC Name:
3-aminopropane-1-sulfonic acid

Test animals

Species:
rabbit
Strain:
not specified

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Number of animals:
No animals used.

Results and discussion

In vivo

Results
Remarks on result:
other: no alert

Applicant's summary and conclusion

Interpretation of results:
other: no alert
Remarks:
Criteria used for interpretation of results: expert judgment
Conclusions:
According to the prediction of Skin irritation delivered by Toxboxes 2.9, no alert came be observed.