Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 244-169-0 | CAS number: 21049-70-7
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Acutely harmful to aquatic invertebrates.
Key value for chemical safety assessment
Additional information
The acute toxicity of 2-(methylamino)ethanol, compound with sulphur dioxide was examined in a GLP guideline study according to OECD 202 with the test species Daphnia magna [BASF AG 2000]. The organisms were exposed to the test substance for 48 hours in a static test system set-up. The stability of the test concentrations over the test period was confirmed by concentration control analytics. At test termination an EC50 of 70.7 mg/L (nominal) was determined.
Additionally, a supporting study with the test substance compound 2-(methylamino)ethanol (CAS 109-83-1) is available which was conducted according to EU Method C.2 with the test organism Daphnia magna [BASF AG 1993]. At test termination after 48 hours an EC50 of 33 mg/L (measured) was determined.
Acute toxicity testing with disodium disulphite (CAS 7681-57-4) and Daphnia magna resulted in an EC50of 74.9 mg/L (nominal, SO3) after 48 h of exposure (guideline study according to 79/831/EEC, appendix V, part C). According to the authors, observed effects were related to oxygen depletion as a result of the oxidation of sulphite.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
