Disodium 6-hydroxy-5-[(4-sulphonatophenyl)azo]naphthalene-2-sulphonate

Short-term toxicity to fish

Description of key information

The lethal concentration (LC50) value ofdisodium 6-hydroxy-5-[(4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonatein fish [Danio rerio] in a 96 hr study on mortality effect was found to be > 100 mg/L.

Thus,considering the CLP Criteria for aquatic classification of the substance , it is concluded thatdisodium 6-hydroxy-5-[(4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonatedoes not exhibit short term toxicity to fish [Danio rerio].

Key value for chemical safety assessment

Fresh water fish

Fresh water fish

Effect concentration:

100 mg/L

Additional information

No. of studies were reviewed for Short-term toxicity to fish from reliable sources having Klimisch rating 2 and 4.

The summary of the results are presented below   

Sr.No	Endpoint	Effect values	Basis for effects	Duration	Species	CAS No.	Sources
1.	LC50	>100 mg/L	Mortality	96 hrs.	danio rerio	Target :2783-94-0	test data
2.	LC50	> 10000 mg/L	Mortality	96 hrs.	Fish	RA CAS: 25956-17-6	Experimental data from publication and study report.
		>1000 mg/L	Mortality	72 hrs.
		200 mg/L	Mortality	48 hrs.
3.	LC50	165 mg/L	Mortality	96 hrs.	Pimephales promelas	RA CAS: 633-96-5	Experimental data from study report.

 

Based on the studies summarized in the above table for the target substance disodium 6-hydroxy-5-[(4-sulphonatophenyl)azo]naphthalene-2-sulphonate and the read across substance, the endpoint value was found to vary between LC50 = >100 mg/L to > 10000 mg/L in a 96 hrs.,at 72 hrs. LC50 = >1000 mg/L and at 48 hrs. LC50 =200 mg/L; on the basis of mortality effect. Based on the above weight of evidence values, the substance it is concluded that the test substance dose not qualifies for the aquatic toxicity.