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Short-term toxicity to aquatic invertebrates

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Description of key information

48h EC50 (Daphnia magna) = 2.8 mg/L (nominal concentration, OECD 202)

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
2.8 mg/L

Additional information

Since only the limited short-term information (24-hour test) involving aquatic invertebrates is available for C16-18AS Na (CAS 68955-20-4), in accordance to Regulation (EC) 1907/2006 Annex XI, 1.5, a read-across to another structurally related category member was conducted. Read-across data from the C12-18AS Na were used (CAS 68955-19-1).

The key study was performed with C12-18AS Na (CAS 68955-19-1) was preformed according OECD guideline 202. A static test with Daphnia magna resulted in the 48-hour EC50 value of 2.8 mg/L (nominal concentrations in agreement with the measured ones).

A supporting study with C12-18 AS Na (CAS 68955-19-1) was performed according to EU Method C.2 and GLP principles (Scholz 1997). Daphnids were exposed to five test concentrations up to 118 mg/L (measured value corresponding to 100 mg/L nominal concentration) for 48 hours under static conditions. The 48-hour EC50 value was determined based on mobility of daphnids as 15 mg/L (nominal concentration).

Moreover, a 24-hour toxicity test with Daphnia magna is available for C16-18AS Na (CAS 68955-20-4; Steber 1988). This test was performed according to DIN 38412, part 11 method. Daphnids were exposed to several concentration of the test substance, no analytical monitoring is available. The 24-hour EC50 value based on mobility was determined to be 275 mg/L (nominal concentrations).

It is expected that the 48-hour EC50 value to aquatic invertebrates of C16-18-AS Na (CAS 68955-20-4) will be comparable to EC50 value of 2.8 mg/L recorded during the C12-18AS Na (CAS 68955-19-1) testing. In conclusion, an 48-hour EC50 of 2.8 mg/L is a reliable value for C16-18-AS Na (CAS 68955-20-4).

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