Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 202-448-4 | CAS number: 95-76-1
Additional ecotoxological information
Administrative data
- Endpoint:
- additional ecotoxicological information
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: only results in EU risk assessment
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Toxikokinetik von 3,4-Dichloranilin beim dreistachligen Stichling (Gasterosteus aculeatus) unter besonderer Berücksichtigung der Fortpflanzungsphysiologie.
- Author:
- Allner B (1997)
- Year:
- 1 997
- Bibliographic source:
- Dissertation am Fachbereich Biologie der Johann Gutenberg-Universität in Mainz.
- Reference Type:
- secondary source
- Title:
- 3,4-dichloroaniline (3,4-DCA)
- Author:
- EU-Risk Assessment Report
- Year:
- 2 006
- Bibliographic source:
- EUR 22235 EN; ISSN 1018-5593
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- no data
- GLP compliance:
- no
Test material
- Reference substance name:
- 3,4-dichloroaniline
- EC Number:
- 202-448-4
- EC Name:
- 3,4-dichloroaniline
- Cas Number:
- 95-76-1
- Molecular formula:
- C6H5Cl2N
- IUPAC Name:
- 3,4-dichloroaniline
Constituent 1
Results and discussion
Any other information on results incl. tables
3,4-DCA is known to have endocrine effects on fish. It could be shown (Allner, 1997) that 3,4-DCA causes lowered androgen synthesis at tested concentrations of 200 and 400 µg/l in breeding male Sticklebacks (Gasterosteus aculeatus). The changes in androgen metabolism are accompanied by changes in the secondary sex characters at concentration of 100, 200 und 400 µg/l. The splendid colour typical of breeding males become regressive and courtship behavior occurs no longer.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
