Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Repeated dose toxicity: via oral route - systemic effects

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
NOAEL
1 000 mg/kg bw/day
Study duration:
subchronic
Species:
rat

Additional information

After oral administration of disodium sebacate on rats for a 6 months period, no mortality and clinical signs were observed. Based on a read across among category members, tetradecanedioic acid is not expected to show subchronic oral toxicity.

Justification for classification or non-classification

Based on the available results, tetradecanedioic acid does not require classification regarding repeated dose toxicity.