Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Well documented study which meets basic scientific principles

Data source

Reference
Reference Type:
publication
Title:
Fast atom bombardment and tandem mass spectrometry for the identification of nucleoside adducts with phenyl glycidyl ether
Author:
Claereboudt J, Esmans EL, van den Eeckhout EG, Claeys M
Year:
1990
Bibliographic source:
Nucleosides & Nucleotides 9(3), 333-344

Materials and methods

Principles of method if other than guideline:
The study deals with the use of fast atom bombardment (FAB) in combination with constant neutral loss (CNL) scanning, high resolution mass spectrometry and tandem mass spectrometry (MS-MS) with collisionally activated decomposition (CAD), as complementary methods for the identification and structural analysis of phenyl glycidyl ether-nucleoside adducts.

Test material

Constituent 1
Reference substance name:
phenyl glycidyl ether
IUPAC Name:
phenyl glycidyl ether
Details on test material:
- Name of test material (as cited in study report): phenyl glycidyl ether
No further information.

Results and discussion

Applicant's summary and conclusion