Registration Dossier
Registration Dossier
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EC number: 204-557-2 | CAS number: 122-60-1
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Scientifically acceptable publication
Data source
Reference
- Reference Type:
- publication
- Title:
- The acute toxicity of some Petrochemicals to Goldfish
- Author:
- Bridie AL, Wolff CJM, Winter M
- Year:
- 1 979
- Bibliographic source:
- Water Research Vol. 13, pages 623-626
Materials and methods
- Principles of method if other than guideline:
- Acute toxicity test following guidlelines released by the American Public Health Association (ALPHA, 1971)
- GLP compliance:
- no
Test material
- Reference substance name:
- 1-phenoxy-2,3-epoxypropane
- IUPAC Name:
- 1-phenoxy-2,3-epoxypropane
- Details on test material:
- - Name of test material (as cited in study report): 1-phenoxy-2,3-epoxypropane
Constituent 1
Test organisms
- Test organisms (species):
- Carassius auratus
- Details on test organisms:
- TEST ORGANISM
- Common name: Goldfish
- Length at study initiation (length definition, mean, range and SD): 6.2 ± 0.7 cm
- Weight at study initiation (mean and range, SD): 3.3 g ± 1.0 g
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Details on test conditions:
- TEST SYSTEM
- Test vessel: glass tanks (42x28x28 cm)
- Fill volume: 25 l
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 1
- No. of vessels per control (replicates): 1
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: local tap water
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
Mortality after 24 and 96 hours
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- 69 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 43 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
