Registration Dossier
Registration Dossier
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EC number: 266-564-7 | CAS number: 67075-37-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anitcipated when introduced in appropriate low concentrations.
Key value for chemical safety assessment
Additional information
The substance belongs to the category of perylene as indicated by its chemical core structure. Based on this structure and the chemical and biological stability of perylenes under environmental conditions data from structural analogue perylenes are used to support the results of the test substance for this endpoint.
The changes in the respiration rate of activated sludge in presence of the analogue perylenes (CAS 4948-15-6, CAS 81-33-4, CAS 128-69-8) were investigated in three guideline studies according to OECD 209 and ISO 8192, respectively, with activated sludge as inoculum. At test termination after 30 minutes effect concentrations > 700 mg/L (nominal) were determined [BASF AG 1998; BASF AG 1999; BASF AG 1986].
Additionally, several oxygen consumption tests which were conducted according to ROBRA (DIN 38412, part 27) are available for the toxicity assessment. The bacteria Pseudomonas putida was exposed to different test concentrations of the following analogue substances: CAS 3049-71-6, CAS 5521-31-3 and CAS 128-69-8 [BASF AG 1991; BASF AG 1990; BASF AG 1986]. After an exposure period of 30 minutes the lowest determined effect concentration was 1250 mg/L (nominal).
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