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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
biodegradation in water: inherent biodegradability
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Conducted according to EU Guideline, however, full details are not provided.
Justification for type of information:
Read-across is considered justified based on the similarity between salicylic acid and the subsalicylate component of bismuth subsalicylate.
Reason / purpose for cross-reference:
read-across source
Qualifier:
according to guideline
Guideline:
EU Method C.9 (Biodegradation: Zahn-Wellens Test)
GLP compliance:
no
Specific details on test material used for the study:
Details on properties of test surrogate or analogue material (migrated information):
No data
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, industrial, non-adapted
Details on inoculum:
No data
Duration of test (contact time):
4 d
Parameter followed for biodegradation estimation:
DOC removal
Details on study design:
This publication details the degradation behaviour of 50 organic substances, including salicylic acid.
The substances were tested under the standard method on a non-adapted activated sludge with 1g/L Total Solids and with a COD (chemical oxygen demand) = 1000 mg/L and DOC (dissolved organic carbon) = 400 mg/L.
Preliminary study:
No data
Test performance:
No data
Parameter:
% degradation (DOC removal)
Value:
> 90
Sampling time:
4 d
Details on results:
Degradation % after time : > 90% in 4 days
Adaptation time (time to 20% degradation) : 1 da
Rate of degradation after adaptation : 27% COD / day
Results with reference substance:
No data
Validity criteria fulfilled:
not specified
Interpretation of results:
inherently biodegradable
Conclusions:
Under the conditions of the study, salicylic acid was inherently biodegradable.
Executive summary:

This study was conducted in accordance with EU Method C.9 (Biodegradation: Zahn-Wellens Test).

Under the conditions of the study, salicylic acid was inherently biodegradable.

Description of key information

By read-across from salicylic acid, the subsalicylate component of the substance is considered to be inherently biodegradable. The concept of biodegradability does not apply to the bismuth component of bismuth subsalicylate.

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information

The concept of biodegradability does not apply to the bismuth component of bismuth subsalicylate. By read-across from salicylic acid, the subsalicylate component of the substance is considered to be inherently biodegradable.