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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

The log Kow is a useful screening tool for many substances, and it is generally assumed that non-ionised organic substances with a log Kow below 3 (4, GHS) are not significantly bioaccumulative (ECHA, 2008).

In accordance with current ECHA guidance (2008), several current models were used for a screening to estimate a BCF (Bioaccumulation factor) for SymHelios® 1031 using either Kow or the aqueous solubility as input parameters. None of the used models predicted BCFs > 1200 L/Kg ww. In addition, the models most applicable to the considered substance predicted BCF values in the range of 33 to 332 L/kg ww well below the PBT or vPvB criteria according to Annex XIII of REACH regulation (i.e., BCF > 2000 L/kg, > 5000 L/kg, respectively). For detailed information please refer to the attached PBT-Assessment report “section 13-IUCLID.

The bioaccumulation potential is one of the criteria used for the PBT/vPvB assessment. A provisional assessment can be made against screening criteria based on the Kow for substances that are expected to accumulate via passive diffusion such as SymHelios® 1031. Furthermore, no specific uptake mechanism apart from lipophilic partitioning is known or suspected. According to ECHA “Guidance on information requirements and chemical safety assessment / Part C: PBT assessment” (May 2008), the criteria for bioaccumulation (B and vB) are not fulfilled, if the logPow is ≤ 4.5.

For organic substances with a log Kow value below 4.5 it is assumed that the affinity for the lipids of an organism is insufficient to exceed the B criterion, i.e. a BCF value of 2000 L/kg ww.

Furthermore, there is no convincing evidence that SymHelios® 1031 can biomagnify in the food chain (BMF < 1). Therefore, the criteria for “bioaccumulating” and for “very bioaccumulating” are not fulfilled.