Registration Dossier
Registration Dossier
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EC number: 638-747-5 | CAS number: 1228186-17-1
Toxicity to soil macroorganisms except arthropods
Administrative data
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Determination of the toxicity of DHTDMAC to the earthworm Eisenia foetida, BIOD/82/06
- Author:
- Coulson et al
- Year:
- 1 989
- Bibliographic source:
- ECETOC Technical Report No. 53, DHTDMAC Aquatic & terrestrial Hazard Assessment
Materials and methods
- Principles of method if other than guideline:
- no details on guideline given
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides
- EC Number:
- 263-090-2
- EC Name:
- Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides
- Cas Number:
- 61789-80-8
- Molecular formula:
- R2Me2N(+)Cl(-) whereas R = mainly C16, 18-alkyl molecular weight range is based on R=14 (lower limit value) and R=18 (higher limit value)
- IUPAC Name:
- N,N-Dimethyl-N,N-di-n-alkyl(C16-18)-ammoniumchloride
- Test material form:
- liquid
- Details on test material:
- 100 % active ingredient (solid) dissolved in methanol, i.e. product (solution in methanol) with 76.1% active ingredient
Constituent 1
Study design
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- yes
- Total exposure duration:
- 14 d
Test conditions
- Details on test conditions:
- no details given
Results and discussion
Effect concentrations
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: mortality, behavioural effects, loss of bodyweight
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- based on assessment within EU RAR on DODMAC (2009)
- Conclusions:
- The toxicity of DHTDMAC to earthwom was tested over 14d at 1000 mg/kg dw. No effects were observed with respect to mortality, behaviour and loss of bodyweight.
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