Registration Dossier
Registration Dossier
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EC number: 201-244-2 | CAS number: 80-04-6
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 18 January 2011 to 01 June 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: Metal Block Method
- Melting / freezing pt.:
- >= 50 - <= 160 °C
- Atm. press.:
- ca. 1 atm
- Decomposition:
- no
- Sublimation:
- no
- Conclusions:
- Rikabinol HB was determined to melt over the range of approximately 50 to 160°C.
Reference
Description of key information
Rikabinol HB was determined to melt over the range of approximately 50 to 160°C.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 50 °C
Additional information
The determination of melting/freezing point of HBPA was carried out by the metal block method (Huntingdon Life Sciences, 2012, Study MOG0004). For confirmatory purposes, differential scanning calorimetry (DSC) was also conducted. The procedure was designed to be compatible with the EC Method A.1 and the OECD test guideline 102, and was conducted in compliance with GLP.
HBPA was determined to melt over the range of approximately 50 to 160 °C.
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