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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1989
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
- EEC directive 84/449 A.6
Deviations:
yes
Remarks:
- The flask method was used instead of the column method because a change in crystal structure might occur when the test substance is deposited on the support material.
GLP compliance:
no
Type of method:
flask method
Water solubility:
0.006 g/L
Temp.:
20 °C
pH:
6.7 - 6.8

Water solubility:

Flask Determination (g/L)
1st 2nd
1 0.00585 0.00615
2 0.00567 0.00568
3 0.00607 0.00597

No evidence of chemical instability

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of test substance was determined to be 0.0059 g/L at 20°C at pH 6.8
Executive summary:

In this guideline (EU A. 6) study, the solubility of the test material (EC 404-360-3) was determined to be 0.0059 g/L at 20°C at pH 6.8

Description of key information

Study conducted to recognised testing guidelines

Key value for chemical safety assessment

Water solubility:
5.9 mg/L
at the temperature of:
20 °C

Additional information

The water solubility was determined by flask method

0.0059 g/L at 20°C at pH 6.8