Hydrogen [4-[4-(p-ethoxyanilino)-4'-[ethyl(m-sulphonatobenzyl)amino]-2'-methylbenzhydrylene]-3-methylcyclohexa-2,5-dien-1-ylidene](ethyl)(m-sulphonatobenzyl)ammonium, monosodium salt

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2014-08-05

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: by loss of weight or by trapping vaporisate

Remarks:

Isothermal Thermogravimetry

Temp.:

20 °C

Vapour pressure:

<= 0.093 Pa

Results:

Due to test item properties (water content ≤ 10 % (w/w)) the sample for the measurement should be dried at 150 °C. The experiment was done applying temperatures from 160 °C to 220 °C. The coefficient of correlation (r²) was 0.9360. The coefficient of correlation (r²) was 0.9981. Extrapolation of the curve to 20 °C and fitting this value in the regression curve, a vapour pressure of   9.34 × 10^-2Pa was obtained (mean of three determinations).

Conclusions:

The vapour pressure of the test item at 20 °C (293K) was: 9.34 × 10E-2 Pa (mean of three determinations, without water).

Executive summary:

The vapour pressure of the test item was determined based on the procedures indicated by the following internationally accepted methods:

- OECD Guideline 104

- EU Method A.4

The purpose of the study was to determine the vapour pressure of the test item using the isothermal thermogravimetrical effusion method. The evaporation rates of the test item at elevated temperatures and ambient pressure were determined by monitoring the weight loss.

The isothermal thermogravimetric effusion method was applied for the determination of the vapour pressure of FAT 20085/B TE. According to Sponsor information (Proposal for Sameness criteria) the test item FAT 20085/B TE consist of ≤ 10 % (w/w) water. Due to test item properties the test was done above 160 °C with a drying phase at 150 °C for 20 min.

Based on the findings of the study, the vapour pressure of the test item at 20 °C (293K) was calculated to: 9.34 × 10^-2 Pa (mean of three determinations, without water).

Description of key information

The vapour pressure of the test item at 20 °C (293K) was calculated to: 9.34 × 10E-2 Pa (mean of three determinations, without water).

Key value for chemical safety assessment

Vapour pressure:

0.093 Pa

at the temperature of:

20 °C

Additional information

The vapour pressure of the test itemwas determined based on the procedures indicated by the following internationally accepted methods:

- OECD Guideline 104

- EU Method A.4

The purpose of the study was to determine the vapour pressure of the test item using the isothermal thermogravimetrical effusion method. The evaporation rates of the test item at elevated temperatures and ambient pressure were determined by monitoring the weight loss.

The isothermal thermogravimetric effusion method was applied for the determination of the vapour pressure of FAT 20085/B TE.According to Sponsor information(Proposal for Sameness criteria) the test item FAT 20085/B TE consist of ≤ 10 % (w/w) water.Due to test item properties the test was done above 160 °C with a drying phase at 150 °C for 20 min.

Based on the findings of the study, the vapour pressure of the test item at 20 °C (293K) was calculated to:9.34 × 10^-2Pa (mean of three determinations, without water).