Registration Dossier

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

In-vitro:

Gene mutation in bacteria

In the key study according to OECD TG 471 and GLP, isopulegol was not mutagenic with and without metabolic activation when tested up to 5000 μg/plate using Salmonella typhimurium TA 1535, TA 100, TA 1537, TA 98 and E. coli WP2 uvrA (BASF2010; 40M0358/10M055).


Short description of key information:
In-vitro Gene mutation in bacteria (AMES acc. to OECD TG 471, GLP): negative (BASF2010; 40M0358/10M055).

Endpoint Conclusion:

Justification for classification or non-classification

The present data on genetic toxicity do not fulfill the criteria laid down in 67/548/EEC and regulation (EU) 1272/2008 and therefore, a non-classification is warranted.