Registration Dossier
Registration Dossier
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EC number: 201-940-6 | CAS number: 89-79-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Additional information
Currently, no study is available for isopulegol to sufficiently cover the endpoint repeated dose toxicity.
In a 14 day feeding study with limitations in documentation an endpoints assessed, diets containing isopulegol at 0.5% or 1% or unsupplemented diet (control) were provided to male Wistar rats (Imaizumi 1985). In this study, relative weights of the liver and concentrations of cholesterol, A-1 and triglyceride were reported to be significantly increased in the 1% isopulegol dose group. According to the authors, the concentration of 0.5% in the diet was calculated to provide an average daily intake of 250 mg isopulegol/kg bw/d.
Justification for classification or non-classification
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