Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 201-940-6 | CAS number: 89-79-2
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- no data
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Secondary literature, peer-reviewed
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 971
- Report date:
- 1971
- Reference Type:
- secondary source
- Title:
- Report to RIFM.
- Author:
- Kligman AM
- Year:
- 1 971
- Bibliographic source:
- Cited in Anonymous (1975). RIFM Monographs on Cosmetic Ingredients. Isopulegol. Food Cosmet Toxicol 13: 823
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- study with volunteers
- Principles of method if other than guideline:
- Maximization test according to
- Kligman AM (1966). The identification of contact allergens by human assay. III. The maximization test. A procedure for screening and rating contact sensitizers. J Invest Derm 47: 393.
- Kligman AM and Epstein W (1975). Updating the maximization test for identifying contact allergens, Contact Dermatitis 1: 231. - GLP compliance:
- no
- Remarks:
- pre-GLP study
Test material
- Reference substance name:
- Isopulegol
- EC Number:
- 201-940-6
- EC Name:
- Isopulegol
- Cas Number:
- 89-79-2
- Molecular formula:
- C10H18O
- IUPAC Name:
- isopulegol
- Details on test material:
- Isopulegol; no further data
Constituent 1
Method
- Type of population:
- not specified
- Route of administration:
- dermal
Results and discussion
- Results of examinations:
- No sensitization reactions were observed.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
